SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:3Tue Dec 13 2016 11:16:33 GMT+0100 (CET)

proteinLength

188

geneLength

564

Gene

Coordinates

1,661,967 → 1,662,533

The protein

Effectors of protein activity

malonyl-CoA and malonyl-[[protein|AcpA|ACP]]]] act as the molecular inducer of the FapR regulon [Pubmed|20201588]

malonyl-CoA and malonyl-[[AcpA|ACP]] act as the molecular inducer of the FapR regulon [Pubmed|20201588]

The protein

Structure

[PDB|2F3X] (complex with effector), [PDB|2F41] [Pubmed|16932747]

[PDB|2F3X] (complex with effector), [PDB|2F41]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

References

Reviews

17919287, 27766255, 15802245, 18372209

17919287, 27766255

References

Original publications

18384517, 20201588, 16932747

[SW|Categories] containing this gene/protein

[SW|biosynthesis of lipids], [SW|transcription factors and their control]

Gene

Coordinates on the chromosome (coding sequence)

1,661,967 -> 1,662,533

The protein

[SW|Interactions]

malonyl-[[AcpA|ACP]]-[[protein|FapR]] [Pubmed|20201588]

Expression and Regulation

Operon

''[[protein|fapR]]-[[protein|plsX]]-[[protein|fabD]]-[[protein|fabG]]-[[protein|acpA]]'' [Pubmed|12737802,19850612]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|16932747]

Expression and Regulation

Regulation

repressed in the absence of malonyl-CoA or malonyl-[[AcpA|ACP]] ([[protein|FapR]]) [Pubmed|20201588]

expressed at high cell density ([[protein|ComA]]) [Pubmed|16091051]

Expression and Regulation

Regulatory mechanism

[[protein|ComA]]: transcription activation ([[protein|ComA]]) [Pubmed|16091051]

[[protein|FapR]]: transcription repression [Pubmed|12737802]